In the case of complete response, follow-up only is required. In cases of residual tumour >3 cm, a PET scan (a minimum of 6 weeks after chemotherapy) is recommended, whereas it is only optional in residual lesion <3 cm (in lesions <3 cm predictive value is less proven).
If PET scan is positive there is strong evidence for residual active tumour and resection should be considered. If PET scan is negative, follow-up only without active treatment is needed. If no PET is done, lesions >3 cm can be either resected or followed only until resolution or progression.
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